The Israeli government is demanding that Apple remove an app called "The Third Palestinian Intifada" from its online store.
The iPhone application, designed by a software company in Dubai, supplies users with information in Arabic on upcoming demonstrations against Israel in the West Bank and on the country's borders, as well as anti-Israel articles and photographs of protesters killed by Israeli security forces.
In a letter sent on Tuesday to Apple founder and CEO Steve Jobs, Minister for Public Affairs and Diaspora in the Prime Minister's Office Yuli Edelstein wrote: "I believe Apple, as a pioneering and progressive company, has the values of liberty, freedom of expression and creativity as a guiding light.
"Also, as a leader in its area, I am convinced that you are aware of this type of application's ability to unite many toward an objective that could be disastrous."
Three months ago, following Mr Edelstein's intervention, Facebook took down a Third Intifada page from its social networking site.
A Prime Minister's Office adviser said on Wednesday that "we have not yet received an answer from Apple although only a day has passed and we are certain they will respond".
