Harold House, Liverpool's Jewish community centre, faces temporary closure unless it can raise £100,000.
The centre is due to move into the new King David schools complex under construction on a neighbouring site and IS scheduled to open in September 2011.
But Harold House chief executive Stephen Simpson warned that the centre cannot continue until then without a cash influx.
"I have to find the funds to keep us going. We are facing a very challenging scenario to find benefactors who will come forward to help us with the work we do looking after the education and well-being of Jewish children," he said.